Research projects

Diet and Alzheimer’s

One of the most complicated issues in clinical AD research is how diet contributes to cognitive decline.  There is also unfortunately a great deal of mythology in this area.As a scientist and physician, let me start by saying that we have no evidence that AD can be cured or slowed...

Research projects

Oxidative stress in Alzheimer’s disease and CAA

One major proposed mechanism to explain changes associated with cellular and organismal aging is that oxidative damage to lipid, protein and nucleic acids accumulates as cells become less capable of coping with oxidative stress.  This potentially leads to membrane instability, accumulation of damaged proteins and acquired mutation, all of which...