Dr. Schrag is a neurologist who focuses on the overlap between vascular and cognitive neurological diseases. His research focuses on the mechanisms of vascular degeneration in cerebral amyloid angiopathy and how this contributes to cognitive impairment in Alzheimer’s disease.

The lab’s goal is to develop a successful treatment for cerebral amyloid angiopathy and Alzheimer’s disease. These two diseases are closely linked, sharing a number of important biological pathways, but unfortunately most recent efforts to treat Alzheimer’s disease have failed because they made the vascular pathology worse.

The lab is searching for a treatment that protects the small blood vessels while improving the plaques and tangles that are associated with Alzheimer’s disease. Dr. Schrag runs a clinic treating patients with cerebral amyloid angiopathy and related diseases like CADASIL and other hereditary small vessel diseases of the brain, fibromuscular dysplasia, cavernous malformation syndromes, and superficial siderosis as we as treating patients with strokes or Alzheimer’s disease.

Patients can be seen in-person in Nashville or remotely in Tennessee and Kentucky.