Recently published results in the Journal of Cerebrovascular Disease further broadens the differential diagnosis of cerebral microhemorrhages. In healthy populations, the vast majority of cerebral microhemorrhages are caused by hypertension and cerebral amyloid angiopathy, but in hospitalized and ill patients, the causes are much more diverse. The authors found that a very high proportion of patients with infective endocarditis had cerebral microhemorrhages whether or not they had neurological symptoms. It was common for patients to have 10 or more microhemorrhages and the distribution was distinctive from both hypertension and cerebral amyloid angiopathy. While no area of the brain was spared, the posterior circulation and in particular the cerebellum were disproportionately involved.
The full manuscript has been posted under the “Lab and Projects” tab.